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Methylene chloride is predominantly used as a solvent. The acute effects of
methylene chloride inhalation in humans consist mainly of nervous system effects including
decreased visual, auditory, and motor functions, but these effects are reversible once exposure
ceases. The effects of chronic (longterm) exposure to methylene chloride suggest that the central
nervous system (CNS) is a potential target in humans and animals. Human data are inconclusive
regarding methylene chloride and cancer. Animal studies have shown increases in liver and lung
cancer and benign mammary gland tumors following the inhalation of methylene chloride.
Uses
* Methylene chloride is predominantly used as a solvent in paint strippers and removers; as a
process solvent in the manufacture of drugs, pharmaceuticals, and film coatings.
* Methylene chloride is also used as a propellant in aerosols for products such as paints,
automotive products, and insect sprays.
* It is used as an extraction solvent for spice oleoresins, hops, and for the removal of caffeine from
coffee. However, due to concern over residual solvent, most decaffeinators no longer use
methylene chloride.
* Methylene chloride is also approved for use as a postharvest fumigant for grains and
strawberries and as a degreening agent for citrus fruit.
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